Detalhe da pesquisa
1.
Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells.
Mol Cell
; 81(17): 3637-3649.e5, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478654
2.
A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors.
Cell
; 151(2): 304-19, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23063122
3.
Reprogramming human T cell function and specificity with non-viral genome targeting.
Nature
; 559(7714): 405-409, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29995861
4.
DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks.
Mol Cell
; 63(4): 633-646, 2016 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27499295
5.
Guide RNA functional modules direct Cas9 activity and orthogonality.
Mol Cell
; 56(2): 333-339, 2014 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25373540
6.
Nucleic acid cleavage with a hyperthermophilic Cas9 from an uncultured Ignavibacterium.
Proc Natl Acad Sci U S A
; 116(46): 23100-23105, 2019 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31659048
7.
Author Correction: Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Nat Methods
; 20(12): 2068, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945910
8.
Mapping the genomic landscape of CRISPR-Cas9 cleavage.
Nat Methods
; 14(6): 600-606, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28459459
9.
Single-cell RNA-seq reveals dynamic paracrine control of cellular variation.
Nature
; 510(7505): 363-9, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24919153
10.
Clinical and pathological impact of VHL, PBRM1, BAP1, SETD2, KDM6A, and JARID1c in clear cell renal cell carcinoma.
Genes Chromosomes Cancer
; 53(1): 38-51, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24166983
11.
An ependymal cell census identifies heterogeneous and ongoing cell maturation in the adult mouse spinal cord that changes dynamically on injury.
Dev Cell
; 58(3): 239-255.e10, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706756
12.
A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function.
Nucleic Acids Res
; 38(21): 7830-44, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20675723
13.
A functional map of HIV-host interactions in primary human T cells.
Nat Commun
; 13(1): 1752, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35365639
14.
Methods Matter: Standard Production Platforms for Recombinant AAV Produce Chemically and Functionally Distinct Vectors.
Mol Ther Methods Clin Dev
; 18: 98-118, 2020 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32995354
15.
Fast-Seq: A Simple Method for Rapid and Inexpensive Validation of Packaged Single-Stranded Adeno-Associated Viral Genomes in Academic Settings.
Hum Gene Ther Methods
; 30(6): 195-205, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855083
16.
Large dataset enables prediction of repair after CRISPR-Cas9 editing in primary T cells.
Nat Biotechnol
; 37(9): 1034-1037, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31359007
17.
A large CRISPR-induced bystander mutation causes immune dysregulation.
Commun Biol
; 2: 70, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30793048
18.
Harnessing type I CRISPR-Cas systems for genome engineering in human cells.
Nat Biotechnol
; 37(12): 1471-1477, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31740839
19.
Crystallographic and in silico analysis of the sialoside-binding characteristics of the Siglec sialoadhesin.
J Mol Biol
; 365(5): 1469-79, 2007 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17137591
20.
Efficient macromolecular crystallization using microfluidics and randomized design of screening reagents.
Methods Mol Biol
; 426: 387-402, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18542878